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Tlaxcala to Guanajuato buses

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Trip Overview

The average bus between Tlaxcala and Guanajuato takes 7h 27m and the fastest bus takes 7h. The bus service runs several times per day from Tlaxcala to Guanajuato. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 27m
Duration
554 km
Distance
$1,240
Average price
4 times a day
Frequency

Tlaxcala to Guanajuato bus times

Buses run 4 times a day between Tlaxcala and Guanajuato. The earliest departure is at 5:40 AM in the morning, and the last departure from Tlaxcala is at 9:40 PM which arrives into Guanajuato at 5:35 AM. All services require a transfer at México TAPO and take an average of 7h 27m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Thursday, November 12, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Friday, November 13, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Saturday, November 14, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Sunday, November 15, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Monday, November 16, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Departing Tuesday, November 17, 2026

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    Autobuses VallesFutura7h 55m • 1 change
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    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h • 1 change
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    Arrives next day

    Autobuses VallesFutura7h 55m • 1 change

Frequently asked questions

Want to know about travelling from Tlaxcala to Guanajuato? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tlaxcala to Guanajuato.ExpandLaunch map view
  • Distance: 553.6 km
  • Duration: 7h 27m

What companies run services between Tlaxcala, Mexico and Guanajuato, Mexico?

You can take a bus from Tlaxcala to Guanajuato via México TAPO, San Lázaro, Pino Suárez, Tasqueña, Terminal Central Del Sur - Taxqueña, and León in around 7h 34m.

Operators