The average bus between Tlaxcala and Oaxaca takes 5h 36m and the fastest bus takes 5h 25m. The bus service runs several times per day from Tlaxcala to Oaxaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Tlaxcala and Oaxaca. The earliest departure is at 6:10 AM in the morning, and the last departure from Tlaxcala is at 10:30 PM which arrives into Oaxaca at 4:30 AM. All services require a transfer, and take on average 5h 36m. The schedules shown below are for the next available departures.

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5h 55m • 1 change

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Want to know about travelling from Tlaxcala to Oaxaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tlaxcala to Oaxaca. However, there are services departing from Tlaxcala station and arriving at Oaxaca station via Oaxaca. The journey, including transfers, takes approximately 5h 36m.
Tlaxcala to Oaxaca bus services, operated by Autobuses Valles, depart from Puebla Terminal CAPU station.
Tlaxcala to Oaxaca bus services, operated by Autobuses Valles, arrive at Oaxaca station.
The distance between Tlaxcala and Oaxaca is 295.1 km. The road distance is 369 km.
ADO operates a bus from Puebla Terminal CAPU to Oaxaca every 2 hours. Tickets cost $700–1,100 and the journey takes 4h 40m.