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Topeka to St. Louis buses

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Trip Overview

The average bus between Topeka and St. Louis takes 6h 37m and the fastest bus takes 6h 15m. The bus service runs several times per day from Topeka to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 37m
Duration
311 mi
Distance
$60
Average price
Twice daily
Frequency

Topeka to St. Louis bus times

Buses run twice daily between Topeka and St. Louis. The earliest departure is at 1:10 AM at night, and the last departure from Topeka is at 6:40 AM which arrives into St. Louis at 12:55 PM. All services run direct with no transfers required, and take on average 6h 37m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Departing Monday, October 12, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Departing Tuesday, October 13, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Departing Wednesday, October 14, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Departing Thursday, October 15, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Departing Friday, October 16, 2026

  •  → 

    bus bus 7h • Direct
  •  → 

    bus bus 6h 15m • Direct

Frequently asked questions

Want to know about travelling from Topeka to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Topeka to St. Louis.ExpandLaunch map view
  • Distance: 311 mi
  • Duration: 6h 37m

What companies run services between Topeka, KS, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Topeka to St Louis Bus Station twice daily. Tickets cost $45–80 and the journey takes 6h 15m.

Operators