The average bus between Tottenham Court Road Station and Southampton Central Station takes 3h 19m and the fastest bus takes 2h 51m. There is a bus service every few hours from Tottenham Court Road Station to Southampton Central Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Tottenham Court Road Station and Southampton Central Station. The earliest departure is at 12:02 AM at night, and the last departure from Tottenham Court Road Station is at 10:26 PM which arrives into Southampton Central Station at 1:30 AM. All services require a transfer at Sloane Square and take an average of 3h 19m. The schedules shown below are for the next available departures.

2h 51m • 1 change

3h 25m • 1 change

3h 16m • 1 change

3h 19m • 1 change

2h 51m • 1 change

3h 25m • 1 change

3h 16m • 1 change

3h 19m • 1 change

2h 57m • 1 change

3h 12m • 1 change

3h 7m • 1 change

3h 14m • 1 change

2h 57m • 1 change

3h 14m • 1 change

3h 11m • 1 change

3h 11m • 1 change
Want to know about travelling from Tottenham Court Road Station to Southampton Central Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tottenham Court Road Station to Southampton Central Station. However, there are services departing from Tottenham Court Road Station station and arriving at Southampton Central Station station via Coach Station station. The journey, including transfers, takes approximately 3h 19m.
Tottenham Court Road Station to Southampton Central Station bus services, operated by Arriva UK, depart from London Victoria station.
Tottenham Court Road Station to Southampton Central Station bus services, operated by Arriva UK, arrive at Coach Station.
The distance between Tottenham Court Road Station and Southampton Central Station is 112.1 km. The road distance is 138 km.
National Express operates a bus from London Victoria to Coach Station hourly. Tickets cost £16–40 and the journey takes 2h 50m.