Rome2Rio

Tuscaloosa to Des Moines buses

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Trip Overview

The bus between Tuscaloosa and Des Moines takes 25h 35m. The bus runs, on average, 6 times per week from Tuscaloosa to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 35m
Duration
1,130 mi
Distance
$269
Average price
6 times a week
Frequency

Tuscaloosa to Des Moines bus times

Buses run 6 times a week between Tuscaloosa and Des Moines. The service departs Tuscaloosa at 9:10 AM in the morning, which arrives into Des Moines at 11:45:00. All services require a transfer at Jackson and take an average of 25h 35m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines25h 35m • 3 changes

Frequently asked questions

Want to know about travelling from Tuscaloosa to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tuscaloosa to Des Moines.ExpandLaunch map view
  • Distance: 1,130 mi
  • Duration: 25h 35m

What companies run services between Tuscaloosa, AL, USA and Des Moines, IA, USA?

You can take a bus from Tuscaloosa Bus Stop to Des Moines via Jackson, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 24h.

Operators