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Tuscaloosa to Louisville buses

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Trip Overview

The average bus between Tuscaloosa and Louisville takes 18h 55m and the fastest bus takes 18h 10m. There is at least one bus per day from Tuscaloosa to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 55m
Duration
627 mi
Distance
$135
Average price
Once daily
Frequency

Tuscaloosa to Louisville bus times

Buses run once daily between Tuscaloosa and Louisville. The service departs Tuscaloosa at 7:45 AM in the morning, which arrives into Louisville at 02:55:00. All services require a transfer at Atlanta Bus Station and take an average of 18h 55m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway18h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Tuscaloosa to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tuscaloosa to Louisville.ExpandLaunch map view
  • Distance: 627 mi
  • Duration: 18h 55m

What companies run services between Tuscaloosa, AL, USA and Louisville, KY, USA?

You can take a bus from Tuscaloosa Bus Stop to Louisville, KY via Atlanta Bus Station and Nashville in around 14h 45m.

Operators