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Tuscaloosa to Opelika buses

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Trip Overview

The average bus between Tuscaloosa and Opelika takes 12h 52m and the fastest bus takes 11h 55m. The bus service runs several times per day from Tuscaloosa to Opelika. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 52m
Duration
335 mi
Distance
$103
Average price
Twice daily
Frequency

Tuscaloosa to Opelika bus times

Buses run twice daily between Tuscaloosa and Opelika. The earliest departure is at 7:45 AM in the morning, and the last departure from Tuscaloosa is at 8:50 PM which arrives into Opelika at 8:45 AM. All services require a transfer at Atlanta Bus Station and take an average of 12h 52m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Departing Friday, November 6, 2026

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    Greyhound USAGreyhound USA13h 50m • 1 change
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    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Departing Saturday, November 7, 2026

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    Greyhound USAGreyhound USA13h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Departing Sunday, November 8, 2026

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    Greyhound USAGreyhound USA13h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Departing Monday, November 9, 2026

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    Greyhound USAGreyhound USA13h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA11h 55m • 1 change

Frequently asked questions

Want to know about travelling from Tuscaloosa to Opelika? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tuscaloosa to Opelika.ExpandLaunch map view
  • Distance: 335.3 mi
  • Duration: 12h 52m

What companies run services between Tuscaloosa, AL, USA and Opelika, AL, USA?

You can take a bus from Tuscaloosa Bus Stop to Opelika 4th Street Station via Atlanta Bus Station, Garnett Station, Doraville Station, and Atlanta in around 8h 16m.

Operators