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Universal Studios Florida to Florida Keys buses

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Trip Overview

The average bus between Universal Studios Florida and Florida Keys takes 15h 2m and the fastest bus takes 9h 52m. There is at least one bus per day from Universal Studios Florida to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 2m
Duration
378 mi
Distance
$78
Average price
Once daily
Frequency

Universal Studios Florida to Florida Keys bus times

Buses run once daily between Universal Studios Florida and Florida Keys. The earliest departure is at 5:18 AM in the morning, and the last departure from Universal Studios Florida is at 11:43 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Universal Blvd & Hollywood Way and take an average of 15h 2m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit12h 52m • 3 changes

Departing Monday, November 2, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit12h 32m • 3 changes

Departing Tuesday, November 3, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit22h 3m • 3 changes
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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit15h 27m • 3 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit23h 3m • 3 changes
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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit15h 27m • 3 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit12h 32m • 3 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit12h 32m • 3 changes

Departing Saturday, November 7, 2026

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    Lynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit9h 52m • 3 changes

Frequently asked questions

Want to know about travelling from Universal Studios Florida to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Universal Studios Florida to Florida Keys.ExpandLaunch map view
  • Distance: 377.5 mi
  • Duration: 15h 2m

What companies run services between Universal Studios Florida, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from Universal Studios Florida to Florida Keys via Universal Blvd & Hollywood Way, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 18m.

Operators