The average bus between University of Southern California and Irvine takes 3h 24m and the fastest bus takes 2h 47m. There is a bus service every few hours from University of Southern California to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between University of Southern California and Irvine. The earliest departure is at 4:06 AM at night, and the last departure from University of Southern California is at 5:01 PM which arrives into Irvine at 8:35 PM. All services require a transfer at Harbor Transitway / 37th St / USC and take an average of 3h 24m. The schedules shown below are for the next available departures.


3h 25m • 2 changes


3h 14m • 2 changes


3h 26m • 2 changes


3h 36m • 2 changes


2h 47m • 2 changes


3h • 2 changes


3h 17m • 2 changes


3h 18m • 2 changes


2h 47m • 2 changes


3h • 2 changes


3h 17m • 2 changes


3h 18m • 2 changes
Want to know about travelling from University of Southern California to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from University of Southern California to Irvine. However, there are services departing from University of Southern California station and arriving at Irvine station via Disneyland Employee's Entrance. The journey, including transfers, takes approximately 3h 24m.
University of Southern California to Irvine bus services, operated by Metro Los Angeles, depart from Harbor Transitway / 37th St / USC station.
University of Southern California to Irvine bus services, operated by Metro Los Angeles, arrive at Main-Harvard station.
The distance between University of Southern California and Irvine is 57.9 km. The road distance is 90 km.
You can take a vehicle from University of Southern California to Main-Harvard via Harbor Transitway / 37th St / USC, Disneyland Employee's Entrance, Harbor-East Shuttle Area, and Artic - Dock 4 in around 3h 38m.