The average bus between Uxbridge and Penzance takes 9h 16m and the fastest bus takes 8h 30m. The bus service runs several times per day from Uxbridge to Penzance. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Uxbridge and Penzance. The earliest departure is at 8:40 AM in the morning, and the last departure from Uxbridge is at 10:35 PM which arrives into Penzance at 7:05 AM. All services require a transfer, and take on average 9h 16m. The schedules shown below are for the next available departures.

9h 7m • 1 change
9h 47m • 1 changeArrives next day

8h 30m • 1 change
9h 54m • 1 change
9h 7m • 1 change
9h 47m • 1 changeArrives next day

8h 30m • 1 change
9h 54m • 1 change
9h 7m • 1 change
9h 47m • 1 changeArrives next day

8h 30m • 1 change
9h 54m • 1 change
9h 10m • 1 change
10h 2m • 1 changeArrives next day

8h 30m • 1 change
9h 13m • 1 change
8h 54m • 1 change
9h 29m • 1 changeArrives next day

8h 30m • 1 changeWant to know about travelling from Uxbridge to Penzance? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Uxbridge to Penzance. However, there are services departing from Uxbridge station and arriving at Penzance station via Bus Station station. The journey, including transfers, takes approximately 9h 16m.
Uxbridge to Penzance bus services, operated by Metroline Travel, depart from Heathrow Central Bus Station.
Uxbridge to Penzance bus services, operated by Metroline Travel, arrive at Bus Station.
The distance between Uxbridge and Penzance is 388.9 km. The road distance is 481 km.
National Express operates a bus from Heathrow Central Bus Station to Bus Station 5 times a day. Tickets cost £55–140 and the journey takes 7h 50m.