The average bus between Vaison-la-Romaine and Lyon takes 6h 28m and the fastest bus takes 5h 25m. The bus service runs several times per day from Vaison-la-Romaine to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Vaison-la-Romaine and Lyon. The earliest departure is at 6:15 AM in the morning, and the last departure from Vaison-la-Romaine is at 5:30 PM which arrives into Lyon at 11:05 PM. All services require a transfer at PEM Gare Routière and take an average of 6h 28m. The schedules shown below are for the next available departures.


5h 35m • 2 changes

5h 25m • 2 changes

5h 59m • 2 changes

6h 35m • 2 changes

5h 35m • 2 changes

5h 25m • 2 changes

5h 59m • 2 changes

6h 35m • 2 changesWant to know about travelling from Vaison-la-Romaine to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Vaison-la-Romaine to Lyon. However, there are services departing from Avenue des Choralies station and arriving at Lyon station via PEM Gare Routière station. The journey, including transfers, takes approximately 6h 28m.
Vaison-la-Romaine to Lyon bus services, operated by ZOU! Proximité, depart from Avenue des Choralies station.
Vaison-la-Romaine to Lyon bus services, operated by FlixBus, arrive at Lyon station.
The distance between Vaison-la-Romaine and Lyon is 168.6 km. The road distance is 201 km.
You can take a bus from Avenue des Choralies to Lyon via PEM Gare Routière and Avignon in around 6h 4m.