The average bus between Van Nuys and Otay Mesa takes 6h 1m and the fastest bus takes 5h 51m. There is at least one bus per day from Van Nuys to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Van Nuys and Otay Mesa. The earliest departure is at 12:18 PM in the afternoon, and the last departure from Van Nuys is at 12:22 PM which arrives into Otay Mesa at 6:19 PM. All services require a transfer at Chandler / Lankershim and take an average of 6h 1m. The schedules shown below are for the next available departures.
Want to know about travelling from Van Nuys to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Van Nuys to Otay Mesa. However, there are services departing from Van Nuys station and arriving at Otay Mesa station via San Diego. The journey, including transfers, takes approximately 6h 1m.
Van Nuys to Otay Mesa bus services, operated by Metro Los Angeles, depart from Los Angeles Union Station.
Van Nuys to Otay Mesa bus services, operated by Metro Los Angeles, arrive at Iris Avenue Transit Center station.
The distance between Van Nuys and Otay Mesa is 225.8 km. The road distance is 263 km.
You can take a bus from Van Nuys / Oxnard to Otay Mesa Rd & Cactus Rd via Chandler / Lankershim, North Hollywood Station, Union Station - Metro B & D Lines, Los Angeles Union Station, San Diego, 12th & Imperial Transit Center, and Iris Avenue Transit Center in around 6h 35m.
