Rome2Rio

Vatican City to Siena buses

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Trip Overview

The average bus between Vatican City and Siena takes 3h 56m and the fastest bus takes 3h 50m. There is at least one bus per day from Vatican City to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 56m
Duration
243 km
Distance
€34
Average price
Once daily
Frequency

Vatican City to Siena bus times

Buses run once daily between Vatican City and Siena. The earliest departure is at 1:07 PM in the afternoon, and the last departure from Vatican City is at 1:19 PM which arrives into Siena at 5:10 PM. All services require a transfer, and take on average 3h 56m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change

Departing Friday, November 13, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 2m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change

Departing Monday, November 16, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 2m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 2m • 1 change

Frequently asked questions

Want to know about travelling from Vatican City to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Vatican City to Siena.ExpandLaunch map view
  • Distance: 243.4 km
  • Duration: 3h 56m

What companies run services between Vatican City and Siena, Italy?

You can take a bus from Giulio Cesare/Ottaviano to Siena via Roma, Autostazione Tiburtina in around 4h 40m.

Operators