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Vatican Museums to Florence buses

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Trip Overview

The average bus between Vatican Museums and Florence takes 4h 17m and the fastest bus takes 3h 46m. There is a bus service every few hours from Vatican Museums to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 17m
Duration
286 km
Distance
€34
Average price
Hourly
Frequency

Vatican Museums to Florence bus times

Buses run hourly between Vatican Museums and Florence. The earliest departure is at 5:43 AM in the morning, and the last departure from Vatican Museums is at 10:23 PM which arrives into Florence at 2:10 AM. All services require a transfer at Dalla Chiesa and take an average of 4h 17m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change

Departing Wednesday, November 11, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 30m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 1m • 1 change
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Departing Thursday, November 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 23m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 30m • 1 change
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Departing Friday, November 13, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 23m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 30m • 1 change
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Departing Saturday, November 14, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 7m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 18m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 37m • 1 change
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Departing Sunday, November 15, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 31m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 6m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 16m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 13m • 1 change
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Departing Monday, November 16, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 27m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 16m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 41m • 1 change
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Frequently asked questions

Want to know about travelling from Vatican Museums to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Vatican Museums to Florence.ExpandLaunch map view
  • Distance: 286.3 km
  • Duration: 4h 17m

What companies run services between Vatican Museums, Vatican City and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators