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Vatican Museums to Florence buses

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Trip Overview

The average bus between Vatican Museums and Florence takes 4h 14m and the fastest bus takes 3h 46m. There is a bus service every few hours from Vatican Museums to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 14m
Duration
286 km
Distance
€30
Average price
Hourly
Frequency

Bus

best
  1. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
4h 38m
€16–44

Vatican Museums to Florence bus times

Buses run hourly between Vatican Museums and Florence. The earliest departure is at 5:43 AM in the morning, and the last departure from Vatican Museums is at 10:23 PM which arrives into Florence at 2:10 AM. All services require a transfer at Dalla Chiesa and take an average of 4h 14m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 41m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàItabus S.p.A.4h 5m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 40m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 51m • 1 change

Departing Saturday, October 10, 2026

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    ATAC S.p.A. Azienda per la mobilitàItabus S.p.A.3h 46m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 57m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 58m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 5m • 1 change
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Departing Sunday, October 11, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 31m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 6m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 16m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 58m • 1 change
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Departing Monday, October 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 23m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 15m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Vatican Museums to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Vatican Museums to Florence.ExpandLaunch map view
  • Distance: 286.3 km
  • Duration: 4h 14m

What companies run services between Vatican Museums, Vatican City and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €22–35 and the journey takes 3h 15m. Three other operators also service this route.

Operators