The average bus between Vatican Museums and Venice takes 9h 20m and the fastest bus takes 7h 24m. The bus service runs several times per day from Vatican Museums to Venice. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Vatican Museums and Venice. The earliest departure is at 6:45 AM in the morning, and the last departure from Vatican Museums is at 11:44 PM which arrives into Venice at 11:55 AM. All services require a transfer at Candia/Mocenigo and take an average of 9h 20m. The schedules shown below are for the next available departures.

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Want to know about travelling from Vatican Museums to Venice? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Vatican Museums to Venice. However, there are services departing from Vatican Museums station and arriving at Venice station via Venezia, Tronchetto. The journey, including transfers, takes approximately 9h 20m.
Vatican Museums to Venice bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Vatican Museums to Venice bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Venezia, Tronchetto station.
The distance between Vatican Museums and Venice is 392.9 km. The road distance is 541 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Venezia, Tronchetto 3 times a day. Tickets cost €40–65 and the journey takes 7h 10m.