Rome2Rio

Venice to Key West buses

Find Transport to Key West

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Venice and Key West takes 22h 2m and the fastest bus takes 21h 37m. The bus runs, on average, 6 times per week from Venice to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 2m
Duration
410 mi
Distance
$78
Average price
6 times a week
Frequency

Venice to Key West bus times

Buses run 6 times a week between Venice and Key West. The earliest departure is at 1:19 PM in the afternoon, and the last departure from Venice is at 3:25 PM which arrives into Key West at 1:02 PM. All services require a transfer at Mall Dr @ Gateway Ave and take an average of 22h 2m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit21h 43m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit23h 43m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit21h 43m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit21h 43m • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit21h 43m • 4 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Sarasota County Area TransitSarasota County Area TransitFlixbus USAGreyhound USAKey West Transit21h 37m • 4 changes

Frequently asked questions

Want to know about travelling from Venice to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Venice to Key West.ExpandLaunch map view
  • Distance: 409.5 mi
  • Duration: 22h 2m

What companies run services between Venice, FL, USA and Key West, FL, USA?

You can take a bus from Venice Train Depot to N Roosevelt & 3rd Street via Mall Dr @ Gateway Ave, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 57m.

Operators