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Vesoul to Lyon buses

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Trip Overview

The average bus between Vesoul and Lyon takes 5h 9m and the fastest bus takes 4h. The bus service runs several times per day from Vesoul to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 9m
Duration
318 km
Distance
€40
Average price
Twice daily
Frequency

Vesoul to Lyon bus times

Buses run twice daily between Vesoul and Lyon. The earliest departure is at 7:30 AM in the morning, and the last departure from Vesoul is at 9:46 PM which arrives into Lyon at 12:40 PM. All services require a transfer, and take on average 5h 9m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Mobigo - DoubsFlixBus4h • 1 change

Departing Thursday, November 5, 2026

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    Mobigo - DoubsFlixBus4h 50m • 1 change
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    Mobigo - DoubsFlixBus4h • 1 change
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    Mobigo - DoubsFlixBus4h 50m • 1 change

Departing Friday, November 6, 2026

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    Mobigo - DoubsFlixBus4h 50m • 1 change
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    Mobigo - DoubsFlixBus4h • 1 change
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    Mobigo - DoubsFlixBus4h 50m • 1 change

Departing Saturday, November 7, 2026

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    Mobigo - DoubsFlixBus5h 10m • 1 change
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    Mobigo - DoubsFlixBus4h • 1 change
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    Mobigo - DoubsFlixBus5h 20m • 1 change
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    Arrives next day

    Mobigo - Haute-SaôneFlixBus14h 54m • 1 change

Departing Sunday, November 8, 2026

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    Mobigo - DoubsFlixBus4h 20m • 1 change
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    Mobigo - DoubsFlixBus4h 50m • 1 change

Departing Monday, November 9, 2026

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    Mobigo - DoubsFlixBus4h 50m • 1 change
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    Mobigo - DoubsFlixBus4h • 1 change
  •  → 

    Mobigo - DoubsFlixBus4h 50m • 1 change

Frequently asked questions

Want to know about travelling from Vesoul to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Vesoul to Lyon.ExpandLaunch map view
  • Distance: 318.2 km
  • Duration: 5h 9m

What companies run services between Vesoul, France and Lyon, France?

You can take a bus from Pôle Multimodal to Lyon via Besançon in around 5h 57m.

Operators