Vesoul to Lyon Buses

Vesoul to Lyon buses

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Trip Overview

The average bus between Vesoul and Lyon takes 5h 37m and the fastest bus takes 4h. The bus service runs several times per day from Vesoul to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 37m
Duration: 288 km
Distance: €35
Average price: 3 times a day
Frequency

Bus

best

Take the bus from Pôle Multimodal to PEM Viottebus 201 / ...
Take the bus from Besançon to Lyonbus 720 / ...

6h 22m

€18–42

Vesoul to Lyon bus times

Buses run 3 times a day between Vesoul and Lyon. The earliest departure is at 7:30 AM in the morning, and the last departure from Vesoul is at 9:46 PM which arrives into Lyon at 12:40 PM. All services require a transfer, and take on average 5h 37m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

8:50 AM → 12:50 PM
4h • 1 change

Departing Thursday, October 15, 2026

7:50 AM → 12:40 PM
4h 50m • 1 change
8:50 AM → 12:50 PM
4h • 1 change
10:50 AM → 5:00 PM
6h 10m • 1 change
6:25 PM → 11:15 PM
4h 50m • 1 change

Departing Friday, October 16, 2026

7:50 AM → 12:40 PM
4h 50m • 1 change
8:50 AM → 12:50 PM
4h • 1 change
10:50 AM → 5:00 PM
6h 10m • 1 change
6:25 PM → 11:15 PM
4h 50m • 1 change

Departing Saturday, October 17, 2026

7:30 AM → 12:40 PM
5h 10m • 1 change
8:50 AM → 12:50 PM
4h • 1 change
10:50 AM → 5:00 PM
6h 10m • 1 change
5:55 PM → 11:15 PM
5h 20m • 1 change
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Departing Sunday, October 18, 2026

10:50 AM → 5:00 PM
6h 10m • 1 change
5:30 PM → 11:15 PM
5h 45m • 1 change

Departing Monday, October 19, 2026

7:50 AM → 12:40 PM
4h 50m • 1 change
10:50 AM → 5:00 PM
6h 10m • 1 change
6:17 PM → 11:15 PM
4h 58m • 1 change

Departing Tuesday, October 20, 2026

7:50 AM → 12:50 PM
5h • 1 change
10:50 AM → 5:00 PM
6h 10m • 1 change

Frequently asked questions

Want to know about travelling from Vesoul to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.