The average bus between Würzburg and Main takes 3h 42m and the fastest bus takes 2h 48m. The bus service runs several times per day from Würzburg to Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Würzburg and Main. The earliest departure is at 4:30 AM at night, and the last departure from Würzburg is at 8:05 PM which arrives into Main at 10:53 PM. All services require a transfer at Frankfurt central train station and take an average of 3h 42m. The schedules shown below are for the next available departures.


4h 11m • 2 changes


3h 14m • 2 changes


4h 43m • 2 changes


2h 48m • 2 changes


4h 40m • 2 changes


3h 6m • 2 changes


4h 43m • 2 changes


3h 41m • 2 changes


4h 4m • 2 changes


3h 14m • 2 changes


4h 39m • 2 changes


2h 48m • 2 changes


4h 4m • 2 changes


3h 14m • 2 changes


4h 39m • 2 changes


2h 48m • 2 changes


4h 4m • 2 changes


3h 14m • 2 changes


4h 39m • 2 changes


3h 41m • 2 changes
Want to know about travelling from Würzburg to Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Würzburg to Main. However, there are services departing from Würzburg station and arriving at Main station via Frankfurt central train station station. The journey, including transfers, takes approximately 3h 42m.
Würzburg to Main bus services, operated by FlixBus, depart from Würzburg Main Station.
Würzburg to Main bus services, operated by FlixBus, arrive at Mainz central train station.
The distance between Würzburg and Main is 120.7 km. The road distance is 157 km.
You can take a bus from Würzburg Main Station to Weisenau, Favorite-Parkhotel via Frankfurt central train station, Mainz central train station, and Mainz, Hauptbahnhof in around 3h 24m.