The average bus between Würzburg and Mannheim takes 3h 42m and the fastest bus takes 3h. The bus service runs several times per day from Würzburg to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Würzburg and Mannheim. The earliest departure is at 4:30 AM at night, and the last departure from Würzburg is at 11:35 PM which arrives into Mannheim at 1:55 AM. All services require a transfer, and take on average 3h 42m. The schedules shown below are for the next available departures.

4h 20m • 1 change

3h • 1 change

2h 25m • 1 change

3h 15m • 1 change

1h 55m • 1 change

3h 15m • 1 change

4h 20m • 1 change

3h • 1 change

1h 55m • 1 change

3h 25m • 1 change

4h 20m • 1 change

3h • 1 change

1h 55m • 1 change

3h 15m • 1 change

4h 20m • 1 change

3h • 1 change

1h 55m • 1 change

3h 25m • 1 change

4h 20m • 1 change

3h • 1 change
Want to know about travelling from Würzburg to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Würzburg to Mannheim. However, there are services departing from Würzburg station and arriving at Mannheim station via Frankfurt central train station station. The journey, including transfers, takes approximately 3h 42m.
Würzburg to Mannheim bus services, operated by FlixBus, depart from Würzburg Main Station.
Würzburg to Mannheim bus services, operated by FlixBus, arrive at Mannheim central bus station.
Book your Würzburg to Mannheim bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Würzburg and Mannheim is 112.1 km. The road distance is 201 km.
You can take a bus from Würzburg Main Station to Mannheim central bus station via Frankfurt central train station in around 3h 2m.