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West Chester to Buffalo buses

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Trip Overview

The average bus between West Chester and Buffalo takes 14h 19m and the fastest bus takes 12h 14m. The bus service runs several times per day from West Chester to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 19m
Duration
429 mi
Distance
$117
Average price
4 times a day
Frequency

Bus via Scranton

best
  1. Take the bus from Philadelphia 30th St Station to Scrantonbus bus Philadelphia
  2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
11h 45m
$100–158

West Chester to Buffalo bus times

Buses run 4 times a day between West Chester and Buffalo. The earliest departure is at 12:33 AM at night, and the last departure from West Chester is at 8:30 PM which arrives into Buffalo at 8:45 AM. All services require a transfer at 69th St Transit Center and take an average of 14h 19m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

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    SEPTASEPTAGreyhound USAFlixbus USA12h 41m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA13h 17m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA12h 15m • 3 changes

Departing Sunday, November 1, 2026

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    SEPTASEPTAGreyhound USAFlixbus USA17h 26m • 3 changes

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    SEPTASEPTAGreyhound USAFlixbus USA18h 2m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA13h 25m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA12h 23m • 3 changes

Departing Monday, November 2, 2026

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    SEPTASEPTAGreyhound USAFlixbus USA15h 12m • 3 changes

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    SEPTASEPTAGreyhound USAFlixbus USA12h 37m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA13h 40m • 3 changes

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    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA12h 14m • 3 changes

Departing Tuesday, November 3, 2026

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    SEPTASEPTAGreyhound USAGreyhound USA15h 37m • 3 changes

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    SEPTASEPTAGreyhound USAFlixbus USA14h 22m • 3 changes

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    Arrives next day

    SEPTASEPTAGreyhound USAFlixbus USA18h • 3 changes

Departing Wednesday, November 4, 2026

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    SEPTASEPTAGreyhound USAGreyhound USA15h 37m • 3 changes

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    SEPTASEPTAGreyhound USAFlixbus USA12h 37m • 3 changes

  •  → 

    Arrives next day

    SEPTASEPTAGreyhound USAFlixbus USA17h 25m • 3 changes

Departing Thursday, November 5, 2026

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    SEPTASEPTAGreyhound USAFlixbus USA15h 12m • 3 changes

  •  → 

    SEPTASEPTAGreyhound USAFlixbus USA12h 37m • 3 changes

  •  → 

    Arrives next day

    SEPTASEPTAFlixbus USAFlixbus USA13h 40m • 3 changes

  •  → 

    Arrives next day

    SEPTASEPTAGreyhound USAFlixbus USA12h 21m • 3 changes
  • Show more

Departing Friday, November 6, 2026

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    SEPTASEPTAGreyhound USAFlixbus USA15h 12m • 3 changes

  •  → 

    SEPTASEPTAGreyhound USAFlixbus USA12h 37m • 3 changes

Frequently asked questions

Want to know about travelling from West Chester to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from West Chester to Buffalo.ExpandLaunch map view
  • Distance: 428.9 mi
  • Duration: 14h 19m

What companies run services between West Chester, PA, USA and Buffalo, NY, USA?

You can take a bus from Chestnut St & Darlington St to Buffalo via 69th St Transit Center, 69th St Transit Center, Drexel Station at 30th St, Philadelphia 30th St Station, and Scranton Bus Station in around 11h 45m.

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