The average bus between West Lafayette, IN and Chicago takes 3h 30m and the fastest bus takes 2h 26m. The bus service runs several times per day from West Lafayette, IN to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between West Lafayette, IN and Chicago. The earliest departure is at 7:43 AM in the morning, and the last departure from West Lafayette, IN is at 11:43 PM which arrives into Chicago at 6:10 AM. All services require a transfer at CityBus Center: BUS215 and take an average of 3h 30m. The schedules shown below are for the next available departures.

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3h 56m • 1 changeWant to know about travelling from West Lafayette, IN to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from West Lafayette, IN to Chicago. However, there are services departing from Lafayette Bus Stop station and arriving at Chicago Bus Station via Chicago Bus Station. The journey, including transfers, takes approximately 3h 30m.
West Lafayette, IN to Chicago bus services, operated by Flixbus USA, depart from Lafayette Bus Stop station.
West Lafayette, IN to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
The distance between West Lafayette, IN and Chicago is 171.6 km. The road distance is 192 km.
Flixbus USA operates a bus from Lafayette Bus Stop to Chicago Bus Station every 4 hours. Tickets cost $19–29 and the journey takes 2h 15m. Greyhound USA also services this route 5 times a day.