Rome2Rio

West Lafayette to Buffalo buses

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Trip Overview

The bus between West Lafayette and Buffalo takes 21h 15m. The bus runs, on average, 5 times per week from West Lafayette to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 15m
Duration
572 mi
Distance
$110
Average price
5 times a week
Frequency

West Lafayette to Buffalo bus times

Buses run 5 times a week between West Lafayette and Buffalo. The service departs West Lafayette at 10:55 PM at night, which arrives into Buffalo at 20:10:00. All services require a transfer, and take on average 21h 15m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Flixbus USAFlixbus USA21h 15m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAFlixbus USA21h 15m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA21h 15m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA21h 15m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA21h 15m • 1 change

Frequently asked questions

Want to know about travelling from West Lafayette to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from West Lafayette to Buffalo.ExpandLaunch map view
  • Distance: 572 mi
  • Duration: 21h 15m

What companies run services between West Lafayette, IN, USA and Buffalo, NY, USA?

You can take a bus from Lafayette Bus Stop to Buffalo via Columbus in around 12h 10m.

Operators