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West Lafayette to St. Louis buses

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Trip Overview

The bus between West Lafayette and St. Louis takes 10h 5m. There is at least one bus per day from West Lafayette to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 5m
Duration
305 mi
Distance
$69
Average price
Once daily
Frequency

West Lafayette to St. Louis bus times

Buses run once daily between West Lafayette and St. Louis. The service departs West Lafayette at 1:45 PM in the afternoon, which arrives into St. Louis at 22:50:00. All services require a transfer, and take on average 10h 5m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Departing Monday, November 9, 2026

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    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Departing Wednesday, November 11, 2026

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    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Departing Thursday, November 12, 2026

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    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Departing Friday, November 13, 2026

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    Amtrak ThruwayGreyhound USA10h 5m • 1 change

Frequently asked questions

Want to know about travelling from West Lafayette to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from West Lafayette to St. Louis.ExpandLaunch map view
  • Distance: 305.3 mi
  • Duration: 10h 5m

What companies run services between West Lafayette, IN, USA and St. Louis, MO, USA?

You can take a bus from Lafayette Amtrak Station to St Louis Bus Station via Indianapolis Union Station in around 6h 15m.

Operators