The average bus between Whitechapel and Southampton takes 3h 54m and the fastest bus takes 3h 2m. There is a bus service every few hours from Whitechapel to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Whitechapel and Southampton. The earliest departure is at 12:08 AM at night, and the last departure from Whitechapel is at 10:48 PM which arrives into Southampton at 2:00 AM. All services require a transfer at Victoria station and take an average of 3h 54m. The schedules shown below are for the next available departures.

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3h 55m • 1 changeWant to know about travelling from Whitechapel to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Whitechapel to Southampton. However, there are services departing from London Green Line Coach Station and arriving at Southampton Central Station via Southampton Central Station. The journey, including transfers, takes approximately 3h 54m.
Whitechapel to Southampton bus services, operated by FlixBus, depart from London Green Line Coach Station.
Whitechapel to Southampton bus services, operated by FlixBus, arrive at Southampton Central Station.
Book your Whitechapel to Southampton bus tickets online with Omio.
The distance between Whitechapel and Southampton is 115.8 km. The road distance is 129 km.
FlixBus operates a bus from London Green Line Coach Station to Southampton Central Station every 3 hours. Tickets cost £10–15 and the journey takes 2h 45m.