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Wiesbaden to Prague buses

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Trip Overview

The average bus between Wiesbaden and Prague takes 22h 37m and the fastest bus takes 22h. There is at least one bus per day from Wiesbaden to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 37m
Duration
549 km
Distance
Kč 1,038
Average price
Once daily
Frequency

Wiesbaden to Prague bus times

Buses run once daily between Wiesbaden and Prague. The earliest departure is at 4:35 AM at night, and the last departure from Wiesbaden is at 5:45 AM which arrives into Prague at 4:45 AM. All services require a transfer, and take on average 22h 37m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    FlixBusRegioJet22h • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    FlixBusRegioJet22h • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    FlixBusRegioJet22h • 1 change

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    FlixBusRegioJet22h • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    FlixBusRegioJet22h • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    FlixBusRegioJet24h 10m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    FlixBusRegioJet24h 10m • 1 change

Frequently asked questions

Want to know about travelling from Wiesbaden to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Wiesbaden to Prague.ExpandLaunch map view
  • Distance: 549.1 km
  • Duration: 22h 37m

What companies run services between Wiesbaden, Germany and Prague, Czechia?

RegioJet operates a bus from Frankfurt Central Train Station to Prague Wilsonova Bus Station once daily. Tickets cost Kč 800–1,300 and the journey takes 6h 15m.

Operators