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Wilkes-Barre to Frederick buses

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Trip Overview

The average bus between Wilkes-Barre and Frederick takes 31h 5m and the fastest bus takes 27h 5m. The bus runs, on average, 4 times per week from Wilkes-Barre to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

31h 5m
Duration
300 mi
Distance
$189
Average price
4 times a week
Frequency

Wilkes-Barre to Frederick bus times

Buses run 4 times a week between Wilkes-Barre and Frederick. The service departs Wilkes-Barre at 5:15 PM in the evening, which arrives into Frederick at 20:20:00. All services require a transfer at Harrisburg Bus Station and take an average of 31h 5m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    TrailwaysGreyhound USABayRunner Shuttle27h 5m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    TrailwaysGreyhound USABayRunner Shuttle27h 5m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    TrailwaysGreyhound USABayRunner Shuttle43h 5m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    TrailwaysGreyhound USABayRunner Shuttle27h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Wilkes-Barre to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Wilkes-Barre to Frederick.ExpandLaunch map view
  • Distance: 300.5 mi
  • Duration: 31h 5m

What companies run services between Wilkes-Barre, PA, USA and Frederick, MD, USA?

You can take a bus from Wilkes Barre, Pa to Frederick via Harrisburg Bus Station and Baltimore in around 9h 20m.

Operators