The bus between Wilkes-Barre and St. Louis takes 22h 55m. There is at least one bus per day from Wilkes-Barre to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Wilkes-Barre and St. Louis. The earliest departure is at 5:15 PM in the evening, and the last departure from Wilkes-Barre is at 5:15 PM which arrives into St. Louis at 3:10 PM. All services require a transfer, and take on average 22h 55m. The schedules shown below are for the next available departures.
Want to know about travelling from Wilkes-Barre to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Wilkes-Barre to St. Louis. However, there are services departing from Wilkes-Barre station and arriving at St. Louis station via Harrisburg, Pa. The journey, including transfers, takes approximately 22h 55m.
Wilkes-Barre to St. Louis bus services, operated by Trailways, depart from Wilkes Barre, Pa station.
Wilkes-Barre to St. Louis bus services, operated by Trailways, arrive at St Louis Bus Station.
Book your Wilkes-Barre to St. Louis bus tickets online with Trailways and Greyhound USA.
The distance between Wilkes-Barre and St. Louis is 1,253.3 km. The road distance is 1,461 km.
You can take a bus from Wilkes Barre, Pa to St Louis Bus Station via Harrisburg Bus Station in around 21h 30m.