The average bus between Williamsburg and Des Moines takes 36h 37m and the fastest bus takes 31h 10m. The bus service runs several times per day from Williamsburg to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Williamsburg and Des Moines. The earliest departure is at 12:45 PM in the afternoon, and the last departure from Williamsburg is at 9:30 PM which arrives into Des Moines at 2:35 PM. All services require a transfer at Washington Union Station and take an average of 36h 37m. The schedules shown below are for the next available departures.
Arrives next day


30h 10m • 2 changes
Arrives +2 days


41h 5m • 2 changes
Arrives next day


30h 10m • 2 changes
Arrives +2 days


41h 5m • 2 changes
Arrives next day


30h 10m • 2 changes
Arrives +2 days


41h 5m • 2 changes
Arrives next day


30h 10m • 2 changes
Arrives +2 days


41h 5m • 2 changes
Want to know about travelling from Williamsburg to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Williamsburg to Des Moines. However, there are services departing from Williamsburg station and arriving at Des Moines station via Washington Union Station station. The journey, including transfers, takes approximately 36h 37m.
Williamsburg to Des Moines bus services, operated by Flixbus USA, depart from Williamsburg Bus Stop station.
Williamsburg to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your Williamsburg to Des Moines bus tickets online with Flixbus USA and Greyhound USA.
The distance between Williamsburg and Des Moines is 1,526.3 km. The road distance is 1,942 km.
You can take a bus from Williamsburg Bus Stop to Des Moines via Washington Union Station and Chicago Bus Station in around 29h.