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Williamsport to Des Moines buses

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Trip Overview

The bus between Williamsport and Des Moines takes 2d. The bus runs, on average, 5 times per week from Williamsport to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,085 mi
Distance
$222
Average price
5 times a week
Frequency

Williamsport to Des Moines bus times

Buses run 5 times a week between Williamsport and Des Moines. The service departs Williamsport at 3:25 PM in the afternoon, which arrives into Des Moines at 14:35:00. All services require a transfer at State College Regional Airport and take an average of 2d. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Fullington TrailwaysFlixbus USAGreyhound USA2d • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Fullington TrailwaysFlixbus USAGreyhound USA2d • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Fullington TrailwaysFlixbus USAGreyhound USA2d • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Fullington TrailwaysFlixbus USAGreyhound USA2d • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Fullington TrailwaysFlixbus USAGreyhound USA2d • 2 changes

Frequently asked questions

Want to know about travelling from Williamsport to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Williamsport to Des Moines.ExpandLaunch map view
  • Distance: 1,085.1 mi
  • Duration: 2d

What companies run services between Williamsport, Lycoming County, PA, USA and Des Moines, IA, USA?

You can take a bus from Williamsport to Des Moines via State College Regional Airport and Chicago Bus Station in around 24h 20m.

Operators