The average bus between Wilmington and Chicago takes 23h 2m and the fastest bus takes 21h 10m. The bus service runs several times per day from Wilmington to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Wilmington and Chicago. The earliest departure is at 1:50 PM in the afternoon, and the last departure from Wilmington is at 8:10 PM which arrives into Chicago at 8:05 PM. All services require a transfer, and take on average 23h 2m. The schedules shown below are for the next available departures.
Arrives next day

20h 10m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

20h 10m • 1 change
Arrives next day

23h 55m • 1 change
Want to know about travelling from Wilmington to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Wilmington to Chicago. However, there are services departing from Wilmington station and arriving at Chicago station via Baltimore Downtown Bus Station station. The journey, including transfers, takes approximately 23h 2m.
Wilmington to Chicago bus services, operated by Greyhound USA, depart from Wilmington Bus Station.
Wilmington to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Book your Wilmington to Chicago bus tickets online with Greyhound USA.
The distance between Wilmington and Chicago is 1,043 km. The road distance is 1,318 km.
You can take a bus from Wilmington Bus Station to Chicago Bus Station via Baltimore Downtown Bus Station in around 20h 55m.