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Winston-Salem to Gainesville buses

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Trip Overview

The bus between Winston-Salem and Gainesville takes 25h 39m. The bus runs, on average, 5 times per week from Winston-Salem to Gainesville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 39m
Duration
528 mi
Distance
$109
Average price
5 times a week
Frequency

Winston-Salem to Gainesville bus times

Buses run 5 times a week between Winston-Salem and Gainesville. The service departs Winston-Salem at 10:20 AM in the morning, which arrives into Gainesville at 11:59:00. All services require a transfer at Charlotte Bus Station and take an average of 25h 39m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA25h 39m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA25h 39m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA25h 39m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA25h 39m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA25h 39m • 2 changes

Frequently asked questions

Want to know about travelling from Winston-Salem to Gainesville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Winston-Salem to Gainesville.ExpandLaunch map view
  • Distance: 528.4 mi
  • Duration: 25h 39m

What companies run services between Winston-Salem, NC, USA and Gainesville, FL, USA?

You can take a bus from Winston Salem(Trans Center) to Gainesville via Charlotte Bus Station and Jacksonville in around 12h 14m.

Operators