The average bus between Winston-Salem and Wilkes-Barre takes 20h 5m and the fastest bus takes 19h 20m. The bus service runs several times per day from Winston-Salem to Wilkes-Barre. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Winston-Salem and Wilkes-Barre. The earliest departure is at 7:10 AM in the morning, and the last departure from Winston-Salem is at 2:55 PM which arrives into Wilkes-Barre at 11:45 AM. All services require a transfer at New York, NY and take an average of 20h 5m. The schedules shown below are for the next available departures.
Arrives next day

19h 20m • 1 change
Arrives next day

20h 50m • 1 change
Arrives next day

19h 20m • 1 change
Arrives next day

20h 50m • 1 change
Arrives next day

19h 20m • 1 change
Arrives next day

20h 50m • 1 change
Want to know about travelling from Winston-Salem to Wilkes-Barre? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Winston-Salem to Wilkes-Barre. However, there are services departing from Winston-Salem station and arriving at Wilkes-Barre station via New York, NY. The journey, including transfers, takes approximately 20h 5m.
Winston-Salem to Wilkes-Barre bus services, operated by Greyhound USA, depart from Winston-Salem, NC station.
Winston-Salem to Wilkes-Barre bus services, operated by Greyhound USA, arrive at Wilkes-Barre station.
Book your Winston-Salem to Wilkes-Barre bus tickets online with Greyhound USA and Martz Bus.
The distance between Winston-Salem and Wilkes-Barre is 686 km. The road distance is 1,230 km.
You can take a bus from Winston-Salem, NC to Wilkes-Barre via New York, NY, East Broadway, 42 St-Bryant Park, and Port Authority Bus Terminal in around 15h 52m.