The average bus between Würzburg and Neu-Isenburg takes 3h 5m and the fastest bus takes 2h 32m. The bus service runs several times per day from Würzburg to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Würzburg and Neu-Isenburg. The earliest departure is at 5:20 AM in the morning, and the last departure from Würzburg is at 11:35 PM which arrives into Neu-Isenburg at 2:55 AM. All services require a transfer at Frankfurt central train station and take an average of 3h 5m. The schedules shown below are for the next available departures.


3h 23m • 2 changes

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2h 47m • 2 changes

4h 8m • 2 changes

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2h 32m • 2 changes

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2h 47m • 2 changes

3h 52m • 2 changesWant to know about travelling from Würzburg to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Würzburg to Neu-Isenburg. However, there are services departing from Würzburg Main Station and arriving at Frankfurt central train station via Frankfurt central train station. The journey, including transfers, takes approximately 3h 5m.
Würzburg to Neu-Isenburg bus services, operated by FlixBus, depart from Würzburg Main Station.
Würzburg to Neu-Isenburg bus services, operated by FlixBus, arrive at Frankfurt central train station.
The distance between Würzburg and Neu-Isenburg is 94.3 km. The road distance is 116 km.
FlixBus operates a bus from Würzburg Main Station to Frankfurt central train station every 3 hours. Tickets cost €10–16 and the journey takes 1h 30m.