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Zephyrhills to Florida Keys buses

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Trip Overview

The average bus between Zephyrhills and Florida Keys takes 31h 51m and the fastest bus takes 24h 15m. The bus runs, on average, 5 times per week from Zephyrhills to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

31h 51m
Duration
472 mi
Distance
$92
Average price
5 times a week
Frequency

Zephyrhills to Florida Keys bus times

Buses run 5 times a week between Zephyrhills and Florida Keys. The earliest departure is at 12:00 PM in the afternoon, and the last departure from Zephyrhills is at 5:00 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Wiregrass Park n Ride and take an average of 31h 51m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Pasco County Public TransportationHillsborough Area Regional TransitUSF Bull RunnerFlixbus USAGreyhound USAKey West Transit43h 15m • 5 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Pasco County Public TransportationHillsborough Area Regional TransitUSF Bull RunnerFlixbus USAGreyhound USAKey West Transit43h 15m • 5 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Pasco County Public TransportationHillsborough Area Regional TransitUSF Bull RunnerFlixbus USAGreyhound USAKey West Transit24h 15m • 5 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Pasco County Public TransportationHillsborough Area Regional TransitUSF Bull RunnerFlixbus USAGreyhound USAKey West Transit24h 15m • 5 changes

Frequently asked questions

Want to know about travelling from Zephyrhills to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Zephyrhills to Florida Keys.ExpandLaunch map view
  • Distance: 472.2 mi
  • Duration: 31h 51m

What companies run services between Zephyrhills, FL, USA and Florida Keys, FL, USA?

You can take a bus from Zephyrhills Downtown Transfer Station to Florida Keys via Wiregrass Park n Ride, UATC to MSC, University of South Florida, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 6m.

Operators