The average train between Acqui Terme and Milan takes 2h 55m and the fastest train takes 2h 44m. The train service runs several times per day from Acqui Terme to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Acqui Terme and Milan. The earliest departure is at 7:37 AM in the morning, and the last departure from Acqui Terme is at 7:37 PM which arrives into Milan at 10:21 PM. All services require a transfer, and take on average 2h 55m. The schedules shown below are for the next available departures.

2h 44m • 1 change

2h 44m • 1 change

3h 57m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

3h 57m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

3h 57m • 1 change

2h 44m • 1 change

3h 2m • 1 change

2h 44m • 1 change

3h 57m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

2h 44m • 1 change

3h 57m • 1 change

2h 44m • 1 change
Want to know about travelling from Acqui Terme to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Acqui Terme to Milan. However, there are services departing from Acqui Terme station and arriving at Milan station via Alessandria. The journey, including transfers, takes approximately 2h 55m.
Acqui Terme to Milan train services, operated by Trenitalia, depart from Acqui Terme station.
Acqui Terme to Milan train services, operated by Trenitalia, arrive at Milan Rogoredo station.
Book your Acqui Terme to Milan train tickets online with Trenitalia and Trenord.
The distance between Acqui Terme and Milan is 104.4 km. The road distance is 126 km.
You can take a train from Acqui Terme to Milan Rogoredo via Alessandria in around 2h 48m.