The average train between Acqui Terme and Santa Margherita Ligure takes 2h 26m and the fastest train takes 1h 58m. There is a train service every few hours from Acqui Terme to Santa Margherita Ligure. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Acqui Terme and Santa Margherita Ligure. The earliest departure is at 5:15 AM in the morning, and the last departure from Acqui Terme is at 8:40 PM which arrives into Santa Margherita Ligure at 10:57 PM. All services require a transfer, and take on average 2h 26m. The schedules shown below are for the next available departures.

2h 34m • 1 change

2h 17m • 1 change

2h 48m • 1 change

1h 59m • 1 change

2h 15m • 1 change

2h 17m • 1 change

2h 48m • 1 change

1h 59m • 1 change

2h 43m • 1 change

2h 15m • 1 change

2h 38m • 1 change

2h 34m • 1 change

2h 43m • 1 change

2h 15m • 1 change

2h 38m • 1 change

2h 34m • 1 change

2h 43m • 1 change

2h 15m • 1 change

2h 38m • 1 change

2h 34m • 1 change
Want to know about travelling from Acqui Terme to Santa Margherita Ligure? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Acqui Terme to Santa Margherita Ligure. However, there are services departing from Acqui Terme station and arriving at Santa Margherita Ligure station via Genova Brignole. The journey, including transfers, takes approximately 2h 26m.
Acqui Terme to Santa Margherita Ligure train services, operated by Trenitalia, depart from Acqui Terme station.
Acqui Terme to Santa Margherita Ligure train services, operated by Trenitalia, arrive at Genova Brignole station.
Book your Acqui Terme to Santa Margherita Ligure train tickets online with Trenitalia, Trenord and Trenitalia Intercity.
The distance between Acqui Terme and Santa Margherita Ligure is 70 km. The road distance is 85 km.
Trenitalia operates a train from Acqui Terme to Genova Brignole hourly. Tickets cost €7–13 and the journey takes 1h 34m.