Amsterdam to Mendrisio Trains

Amsterdam to Mendrisio trains

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Trip Overview

The average train between Amsterdam and Mendrisio takes 14h 14m and the fastest train takes 11h 38m. The train service runs several times per day from Amsterdam to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 14m
Duration: 1,021 km
Distance: CHF 192
Average price: 5 times a day
Frequency

Train

best

Take the train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbftrain Ice
Take the train from Frankfurt to Basel SBBtrain 43
Take the train from Basel SBB to Luganotrain Ec

11h 16m

CHF 92–317

Amsterdam to Mendrisio train times

Trains run 5 times a day between Amsterdam and Mendrisio. The earliest departure is at 6:38 AM in the morning, and the last departure from Amsterdam is at 6:38 PM which arrives into Mendrisio at 2:18 PM. All services require a transfer at Frankfurt and take an average of 14h 14m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

6:38 PM → 2:18 PM
Arrives next day
19h 40m • 3 changes

Departing Thursday, November 5, 2026

6:38 AM → 6:18 PM
11h 40m • 3 changes
8:31 AM → 8:18 PM
11h 47m • 3 changes
10:31 AM → 10:27 PM
11h 56m • 3 changes
12:38 PM → 12:27 AM
Arrives next day
11h 49m • 3 changes
Show more

Departing Friday, November 6, 2026

6:38 AM → 6:18 PM
11h 40m • 3 changes
8:31 AM → 8:18 PM
11h 47m • 3 changes
10:31 AM → 10:27 PM
11h 56m • 3 changes
12:33 PM → 12:27 AM
Arrives next day
11h 54m • 3 changes
Show more

Departing Saturday, November 7, 2026

6:38 AM → 6:18 PM
11h 40m • 3 changes
8:31 AM → 8:18 PM
11h 47m • 3 changes
10:31 AM → 10:27 PM
11h 56m • 3 changes
12:33 PM → 12:27 AM
Arrives next day
11h 54m • 3 changes
Show more

Departing Sunday, November 8, 2026

6:40 AM → 6:18 PM
11h 38m • 3 changes
8:31 AM → 8:18 PM
11h 47m • 3 changes
12:33 PM → 12:27 AM
Arrives next day
11h 54m • 3 changes
2:33 PM → 10:18 AM
Arrives next day
19h 45m • 3 changes
Show more

Departing Monday, November 9, 2026

6:38 AM → 6:18 PM
11h 40m • 3 changes
8:31 AM → 8:18 PM
11h 47m • 3 changes
10:31 AM → 10:27 PM
11h 56m • 3 changes
12:38 PM → 12:27 AM
Arrives next day
11h 49m • 3 changes
Show more

Departing Tuesday, November 10, 2026

8:01 AM → 8:18 PM
12h 17m • 3 changes
10:01 AM → 10:27 PM
12h 26m • 3 changes

Frequently asked questions

Want to know about travelling from Amsterdam to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.