The average train between Ann Arbor and Lisle takes 6h 12m and the fastest train takes 5h 40m. The train service runs several times per day from Ann Arbor to Lisle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Ann Arbor and Lisle. The earliest departure is at 7:14 AM in the morning, and the last departure from Ann Arbor is at 7:00 PM which arrives into Lisle at 12:29 AM. All services require a transfer, and take on average 6h 12m. The schedules shown below are for the next available departures.

5h 15m • 1 change

4h 40m • 1 change
Arrives next day

5h 29m • 1 change

5h 15m • 1 change

4h 40m • 1 change
Arrives next day

5h 29m • 1 change

5h 15m • 1 change

4h 40m • 1 change
Arrives next day

5h 29m • 1 change

5h 15m • 1 change

4h 40m • 1 change
Arrives next day

5h 29m • 1 change

5h 15m • 1 change

5h 6m • 1 change
Arrives next day

5h 29m • 1 change
Want to know about travelling from Ann Arbor to Lisle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ann Arbor to Lisle. However, there are services departing from Ann Arbor station and arriving at Lisle station via Chicago Union Station station. The journey, including transfers, takes approximately 6h 12m.
Ann Arbor to Lisle train services, operated by Amtrak, depart from Ann Arbor Amtrak Station.
Ann Arbor to Lisle train services, operated by Amtrak, arrive at Chicago Union Station.
The distance between Ann Arbor and Lisle is 361.8 km. The road distance is 429 km.
Amtrak operates a train from Ann Arbor Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $75–160 and the journey takes 4h 18m.