The average train between Antwerp and La Défense takes 3h 3m and the fastest train takes 2h 22m. The train service runs several times per day from Antwerp to La Défense. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Antwerp and La Défense. The earliest departure is at 7:33 AM in the morning, and the last departure from Antwerp is at 8:33 PM which arrives into La Défense at 11:10 PM. All services require a transfer at Paris Nord and take an average of 3h 3m. The schedules shown below are for the next available departures.

2h 53m • 1 change

2h 48m • 1 change

2h 59m • 1 change
Arrives next day

9h 7m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 59m • 1 change

3h 15m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 59m • 1 change

3h 15m • 1 change

2h 48m • 1 change

2h 59m • 1 change

2h 52m • 1 change

2h 52m • 1 change

2h 48m • 1 change

2h 52m • 1 change

2h 52m • 1 change

2h 56m • 1 change

2h 22m • 1 change

2h 41m • 1 change

2h 41m • 1 change

2h 41m • 1 change
Want to know about travelling from Antwerp to La Défense? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Antwerp to La Défense. However, there are services departing from Antwerp station and arriving at La Défense station via Paris Nord. The journey, including transfers, takes approximately 3h 3m.
Antwerp to La Défense train services, operated by Eurostar, depart from Anvers-Central station.
Antwerp to La Défense train services, operated by Eurostar, arrive at Paris Nord station.
The distance between Antwerp and La Défense is 301.4 km. The road distance is 366 km.
Eurostar operates a train from Anvers-Central to Paris Nord hourly. Tickets cost €100–180 and the journey takes 2h 5m.