The average train between Anzio and Siena takes 5h 56m and the fastest train takes 4h 19m. There is a train service every few hours from Anzio to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Anzio and Siena. The earliest departure is at 4:58 AM at night, and the last departure from Anzio is at 10:04 PM which arrives into Siena at 9:38 AM. All services require a transfer at Roma Termini and take an average of 5h 56m. The schedules shown below are for the next available departures.


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4h 24m • 2 changesWant to know about travelling from Anzio to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Anzio to Siena. However, there are services departing from Anzio Colonia station and arriving at Siena station via Roma Termini station and Firenze S.M.N. station. The journey, including transfers, takes approximately 5h 56m.
Anzio to Siena train services, operated by Trenitalia, depart from Anzio Colonia station.
Anzio to Siena train services, operated by Trenitalia, arrive at Siena station.
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The distance between Anzio and Siena is 233 km. The road distance is 289 km.
You can take a train from Anzio Colonia to Siena via Roma Termini and Firenze S.M.N. in around 5h 22m.