The average train between Ascoli Piceno and Brindisi takes 7h 27m and the fastest train takes 5h 7m. The train service runs several times per day from Ascoli Piceno to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Ascoli Piceno and Brindisi. The earliest departure is at 9:06 AM in the morning, and the last departure from Ascoli Piceno is at 7:15 PM which arrives into Brindisi at 6:21 AM. All services require a transfer at San Benedetto Tronto and take an average of 7h 27m. The schedules shown below are for the next available departures.


7h 32m • 2 changes


7h 18m • 2 changes


6h 4m • 2 changes


6h 3m • 2 changes


7h 32m • 2 changes


7h 18m • 2 changes


6h 4m • 2 changes


6h 3m • 2 changes


7h 32m • 2 changes


7h 42m • 2 changes


6h 4m • 2 changes


6h 3m • 2 changes


7h 28m • 2 changes


7h 38m • 2 changes


6h 4m • 2 changes


6h 3m • 2 changes


6h 5m • 2 changes


6h 22m • 2 changes


5h 7m • 2 changes


5h 17m • 2 changes
Want to know about travelling from Ascoli Piceno to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ascoli Piceno to Brindisi. However, there are services departing from Ascoli Piceno station and arriving at Brindisi station via Bari Centrale. The journey, including transfers, takes approximately 7h 27m.
Ascoli Piceno to Brindisi train services, operated by Trenitalia, depart from San Benedetto Tronto station.
Ascoli Piceno to Brindisi train services, operated by Trenitalia, arrive at Brindisi station.
Book your Ascoli Piceno to Brindisi train tickets online with Trenitalia, Trenitalia Intercity and Trenitalia Frecce.
The distance between Ascoli Piceno and Brindisi is 438.1 km. The road distance is 500 km.
You can take a train from Ascoli Piceno to Brindisi via San Benedetto Tronto and Bari Centrale in around 5h 37m.