The average train between Ascoli Piceno and Milan takes 6h 25m and the fastest train takes 5h. The train service runs several times per day from Ascoli Piceno to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Ascoli Piceno and Milan. The earliest departure is at 5:30 AM in the morning, and the last departure from Ascoli Piceno is at 8:52 PM which arrives into Milan at 9:50 AM. All services require a transfer at San Benedetto Tronto and take an average of 6h 25m. The schedules shown below are for the next available departures.


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6h 18m • 2 changesWant to know about travelling from Ascoli Piceno to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ascoli Piceno to Milan. However, there are services departing from San Benedetto Tronto station and arriving at Milano Centrale station via Bologna Centrale station. The journey, including transfers, takes approximately 6h 25m.
Ascoli Piceno to Milan train services, operated by Trenitalia Frecce, depart from San Benedetto Tronto station.
Ascoli Piceno to Milan train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
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The distance between Ascoli Piceno and Milan is 454.4 km. The road distance is 539 km.
You can take a train from Ascoli Piceno to Milano Centrale via San Benedetto Tronto and Bologna Centrale in around 5h 2m.