The average train between Assen and Brussels takes 4h 27m and the fastest train takes 3h 58m. There is a train service every few hours from Assen to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Assen and Brussels. The earliest departure is at 6:05 AM in the morning, and the last departure from Assen is at 11:05 PM which arrives into Brussels at 8:11 AM. All services require a transfer, and take on average 4h 27m. The schedules shown below are for the next available departures.

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4h 1m • 1 changeWant to know about travelling from Assen to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Assen to Brussels. However, there are services departing from Assen station and arriving at Brussels station via Schiphol Airport Train Station station. The journey, including transfers, takes approximately 4h 27m.
Assen to Brussels train services, operated by Nederlandse Spoorwegen (NS), depart from Assen station.
Assen to Brussels train services, operated by Nederlandse Spoorwegen (NS), arrive at Brussel-Zuid station.
Book your Assen to Brussels train tickets online with Nederlandse Spoorwegen (NS).
The distance between Assen and Brussels is 282.8 km. The road distance is 378 km.
You can take a train from Assen to Brussel-Zuid via Schiphol Airport Train Station in around 4h.