The average train between Avezzano and Siena takes 7h 40m and the fastest train takes 5h 37m. The train service runs several times per day from Avezzano to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Avezzano and Siena. The earliest departure is at 5:03 AM in the morning, and the last departure from Avezzano is at 6:38 PM which arrives into Siena at 7:47 AM. All services require a transfer at Roma Tiburtina and take an average of 7h 40m. The schedules shown below are for the next available departures.


5h 37m • 2 changes


6h 23m • 2 changes


6h 18m • 2 changes


6h 28m • 2 changes


5h 37m • 2 changes


6h 23m • 2 changes


6h 18m • 2 changes


6h 28m • 2 changes


5h 37m • 2 changes


6h 23m • 2 changes


6h 18m • 2 changes


6h 28m • 2 changes


5h 37m • 2 changes


6h 23m • 2 changes


6h 18m • 2 changes


6h 28m • 2 changes
Want to know about travelling from Avezzano to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avezzano to Siena. However, there are services departing from Avezzano station and arriving at Siena station via Roma Tiburtina. The journey, including transfers, takes approximately 7h 40m.
Avezzano to Siena train services, operated by Trenitalia, depart from Avezzano station.
Avezzano to Siena train services, operated by Trenitalia, arrive at Siena station.
Book your Avezzano to Siena train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Avezzano and Siena is 223.4 km. The road distance is 454 km.
You can take a train from Avezzano to Siena via Roma Tiburtina and Firenze S.M.N. in around 5h 49m.