The average train between Avignon and Sisteron takes 4h 44m and the fastest train takes 2h 50m. The train service runs several times per day from Avignon to Sisteron. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Avignon and Sisteron. The earliest departure is at 12:20 AM at night, and the last departure from Avignon is at 11:59 PM which arrives into Sisteron at 9:49 AM. All services require a transfer, and take on average 4h 44m. The schedules shown below are for the next available departures.

9h 29m • 1 change
2h 53m • 1 change
3h 15m • 1 change
2h 50m • 1 changeWant to know about travelling from Avignon to Sisteron? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avignon to Sisteron. However, there are services departing from Avignon Tgv station and arriving at Sisteron station via Marseille St Charles station. The journey, including transfers, takes approximately 4h 44m.
Avignon to Sisteron train services, operated by TGV inOui, depart from Avignon Tgv station.
Avignon to Sisteron train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Sisteron station.
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The distance between Avignon and Sisteron is 94.8 km. The road distance is 121 km.
You can take a train from Avignon Tgv to Sisteron via Marseille St Charles in around 3h 28m.