The average train between Avignon and Toulouse takes 4h 28m and the fastest train takes 3h 35m. The train service runs several times per day from Avignon to Toulouse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Avignon and Toulouse. The earliest departure is at 7:17 AM in the morning, and the last departure from Avignon is at 9:33 PM which arrives into Toulouse at 9:12 AM. All services require a transfer, and take on average 4h 28m. The schedules shown below are for the next available departures.

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change
Want to know about travelling from Avignon to Toulouse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avignon to Toulouse. However, there are services departing from Avignon station and arriving at Toulouse station via Nimes. The journey, including transfers, takes approximately 4h 28m.
Avignon to Toulouse train services, operated by Zou! Lignes Express Régionales, depart from Avignon Centre station.
Avignon to Toulouse train services, operated by Zou! Lignes Express Régionales, arrive at Toulouse Matabiau station.
Book your Avignon to Toulouse train tickets online with Zou! Lignes Express Régionales, TGV inOui and Société Nationale des Chemins de fer Français (SNCF).
The distance between Avignon and Toulouse is 272.9 km. The road distance is 345 km.
You can take a train from Avignon Centre to Toulouse Matabiau via Nimes in around 3h 42m.