The average train between Brent and Manchester takes 2h 44m and the fastest train takes 2h 35m. The train runs at least 2 times per hour from Brent to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Brent and Manchester. The earliest departure is at 5:39 AM in the morning, and the last departure from Brent is at 9:26 PM which arrives into Manchester at 12:39 AM. All services require a transfer, and take on average 2h 44m. The schedules shown below are for the next available departures.

2h 46m • 1 change

2h 49m • 1 change

2h 53m • 1 change

2h 38m • 1 change
Want to know about travelling from Brent to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brent to Manchester. However, there are services departing from Brent station and arriving at Manchester station via Manchester Piccadilly. The journey, including transfers, takes approximately 2h 44m.
Brent to Manchester train services, operated by London Overground, depart from London Euston station.
Brent to Manchester train services, operated by London Overground, arrive at Manchester Piccadilly station.
Book your Brent to Manchester train tickets online with London Overground and Avanti West Coast.
The distance between Brent and Manchester is 251.2 km. The road distance is 307 km.
Avanti West Coast operates a train from London Euston to Manchester Piccadilly every 30 minutes. Tickets cost £65–110 and the journey takes 2h 12m.