The average train between Brentford and Holyhead takes 5h and the fastest train takes 4h 38m. The train service runs several times per day from Brentford to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brentford and Holyhead. The earliest departure is at 7:05 AM in the morning, and the last departure from Brentford is at 6:52 PM which arrives into Holyhead at 11:53 PM. All services require a transfer at Vauxhall and take an average of 5h. The schedules shown below are for the next available departures.


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Want to know about travelling from Brentford to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brentford to Holyhead. However, there are services departing from Brentford station and arriving at Holyhead station via Holyhead. The journey, including transfers, takes approximately 5h.
Brentford to Holyhead train services, operated by South Western Railway, depart from London Euston station.
Brentford to Holyhead train services, operated by South Western Railway, arrive at Holyhead station.
Book your Brentford to Holyhead train tickets online with South Western Railway, London Underground (Tube) and Avanti West Coast.
The distance between Brentford and Holyhead is 355.9 km. The road distance is 444 km.
Avanti West Coast operates a train from London Euston to Holyhead 5 times a day. Tickets cost £95–160 and the journey takes 3h 52m.