The average train between Brentford and Manchester takes 3h 17m and the fastest train takes 2h 56m. There is an hourly train service from Brentford to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Brentford and Manchester. The earliest departure is at 12:22 AM at night, and the last departure from Brentford is at 11:55 PM which arrives into Manchester at 8:25 AM. All services require a transfer at Vauxhall and take an average of 3h 17m. The schedules shown below are for the next available departures.


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3h • 2 changesWant to know about travelling from Brentford to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brentford to Manchester. However, there are services departing from London Euston station and arriving at Manchester Piccadilly station via Manchester Piccadilly station. The journey, including transfers, takes approximately 3h 17m.
Brentford to Manchester train services, operated by Avanti West Coast, depart from London Euston station.
Brentford to Manchester train services, operated by Avanti West Coast, arrive at Manchester Piccadilly station.
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The distance between Brentford and Manchester is 256.9 km. The road distance is 294 km.
Avanti West Coast operates a train from London Euston to Manchester Piccadilly every 30 minutes. Tickets cost £60–100 and the journey takes 2h 12m.