The average train between Brentford and Southampton takes 2h 8m and the fastest train takes 1h 56m. The train runs at least 2 times per hour from Brentford to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Brentford and Southampton. The earliest departure is at 12:22 AM at night, and the last departure from Brentford is at 11:55 PM which arrives into Southampton at 7:00 AM. All services require a transfer, and take on average 2h 8m. The schedules shown below are for the next available departures.

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2h 1m • 1 changeWant to know about travelling from Brentford to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brentford to Southampton. However, there are services departing from Syon Lane station and arriving at Southampton Central station via London Waterloo station. The journey, including transfers, takes approximately 2h 8m.
Brentford to Southampton train services, operated by South Western Railway, depart from Syon Lane station.
Brentford to Southampton train services, operated by South Western Railway, arrive at Southampton Central station.
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The distance between Brentford and Southampton is 99.4 km. The road distance is 113 km.
You can take a train from Syon Lane to Southampton Central via London Waterloo in around 2h 15m.